Fluorinated Phenylalanine Precursor Resistance in Yeast
Development of a counter-selection method for phenylalanine auxotrophy could be a useful tool in the repertoire of yeast genetics.Fluorinated and sulfurated precursors of phenylalanine were tested for toxicity in Saccharomyces cerevisiae.One such precursor, 4-fluorophenylpyruvate (FPP), was found to be toxic to several strains from the Saccharomyce